1. leave or desert sb. 拋棄
His former allies ran out on him. 他原來的伙伴們拋棄了他。
2. fail to fulfil;withdraw one's support from 不履行;遺棄;不予支持
You can not run out on the contract,or you could be taken to court. 你不能不履行合同,否則你要上法庭的。
He said he would help us, but at the last moment he ran out on us. 他說他要幫我們的忙,但最後他卻不管我們了。
No one could accuse him of running out on his friends. 沒人可以責備他不幫朋友忙。